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The Valve for a Lifetime
Perceval Plus is based on the trusted Perceval Platform
The Perceval Platform is based on a sutureless and collapsible design that simplifies the surgical implantation, reducing the impact of surgery and facilitating faster recovery.1,2
Introducing LANCELOT Technology. LANCELOT delivers enhanced hemodynamics through the integration of precision laser cutting and after zero-pressure shaping.*
The innovative FREE Tissue Treatment in Perceval Plus addresses both major causes of valve calcification, phospholipids and aldehydes. The technology also allows the valve to be stored in an aldehyde-free solution, resulting in negligible toxicity for the patient and a faster procedure for the surgeon as no rinsing is required.3
FREE is designed to improve durability.3
* vs control group
Szecel D. et al. - Abstract presented at SCTS Annual Meeting 2025
Superlastic stent
Double sheet design
An outer sheet acts as a cushion that minimizes stress transferred to the leaflets.
Fully atraumatic collapsing
The collapsing procedure does not affect the leaflets preventing any possible damage to the tissue.8
Perceval Plus is based on the trusted Perceval Platform, that has shown a linearized rate of SVD of 0.74% per patient-years with a maximum follow-up of 15 years.9
* Technical claims are supported by CORCYM data on file. Data related to bench tests
Perceval Plus boasts a distinctive design built around a superelastic stent that self-expands in place (no need to knot the sutures), ensuring optimal valve sealing.2
The Nitinol stent allows Perceval Plus to follow the physiological movement of the aortic root during the cardiac cycle, mimicking the native valve.10,11
Perceval Plus is a valve designed for the future. Not only is it durable,9 but it also gives patients even broader treatment options for their future. Its exclusive stent design allows even circumferential expansion to accommodate future transcatheter valves, making Perceval Plus ViV friendly by design. Thanks to its unique features, all patients eligible for biological AVR may benefit from a Perceval Plus implant.**12,13
Clear visibility
The Nitinol stent provides clear visibility under fluoroscopy and CT scan to identify landmarks which facilitate the ViV procedure.
Even circumferential expansion
The inflow ring can be evenly and circumferentially expanded up to 2.5mm above its nominal size, which allows for hemodynamic advantages and greater compatibility with TAVI models and sizes.
Minimized risk of coronary obstruction
Perceval Plus leaflets remain open when a TAVI is deployed inside it. The sinusoidal struts and the open leaflets create a space between the coronary ostia and the leaflets themselves wich is preserved even after the TAVI deployment.
Minimized risk of sinus sequestration
By design, the Perceval Plus leaflets, when open, do not touch the STJ, thus avoiding sinus sequestration.
Perceval Plus and Minimally Invasive Cardiac Surgery were made for each other thanks to the sutureless design of the valve and the length and diameter of the new Deliver System. The System allows for minimized incision,11,15 maximized visibility11,12, faster learning curve14,15 and a reduced manipulation of the aortic root.11,15,16
Minimized incision11,12
Thanks to the unique collapsible profile and sutureless design of the valve and the design of the Delivery System, Perceval Plus allows a reduced incision size and less surgical trauma.2,11,17
Maximized visibility during implantation11,12
The collapsible profile of the valve and the small diameter of the Delivery System allow the surgeon full visibility of the annulus and of the anatomical structures during implantation and deployment for great confidence and fast, precise positioning at the implantation site.2,8
Fast-track surgery and ERAS have demonstrated many benefits for both the patient18-20 and the hospital.18,20-23 Perceval Plus’s unique design and proven clinical benefits2,17 are expected to enhance the advantages of fast-track and ERAS (Enhanced Recovery After Surgery) protocols even further. Compared to conventional valves, Perceval Plus has shown many advantages, both in full sternotomy and MICS approaches:12,13,17
Take sutureless AVR to the next level with Perceval Plus and the RelyON accessories System. Perceval Plus is now accompanied by RelyON creating a comprehensive System that allows for a smooth experience for the whole OR team. RelyON has been designed in partnership with surgeons and nurses to ensure an easy and fast Perceval Plus procedure, from unboxing to deployment.
Precise
The RelyON Delivery System delivers Perceval Plus with a single movement of the hand allowing to maintain a firm hold on the device, which in turn facilitates a precise positioning of the valve in the aortic root.
User-friendly
Top-loading valve, self-locking lever, infographics, open-close guide, all-in-one packaging allow for a calm procedure and empower any user to prepare the valve in a quick and effective way.
Optimized for MICS procedures
The design of the Delivery System is optimized for MICS. Both the length and the small diameter of the shaft, together with the collapsible design of Perceval Plus, allow for a minimized incision and facilitated access to and visualization of the implantation site.
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